N4 Pharma Plc (LON: N4P), the specialist pharmaceutical company developing Nuvec®, a novel delivery system for cancer treatments and vaccines, has provided a positive update on its ongoing oral delivery research work.
The Company through its research program with the University of Queensland is evaluating the potential of Nuvec® to act as an oral delivery system for oligonucleotides including DNA and RNA.
Experiments have now confirmed, in vivo, the successful oral administration of Nuvec® loaded with a DNA plasmid for ovalbumin. The Nuvec® was administered by enteric coated capsule and the contents, having been released in the intestinal lumen, were taken up by intestinal cells, with successful transfection and release of the newly synthesized ovalbumin.
