N4 Pharma Plc (LON:N4P), the specialist pharmaceutical company developing Nuvec®, a novel delivery system for cancer treatments, gene therapy and vaccines, has provided a further encouraging update on its ongoing in vitro siRNA research work.
The Company has now completed its in-vitro experiments combining EGFR (epidermal growth factor receptor) and PLK1 (Polo Like Kinase 1) siRNA molecules onto the same Nuvec® nanoparticle and testing it in PC9 lung cancer cells.
The work clearly shows that there is a strong beneficial effect at 48 hours on cellular inhibition compared to single dose siRNA, by combining both EGFR and PLK1 onto the same particle.
