Research published in the journal Molecules, found 6 common artificial sweeteners approved by the Food and Drug Administration and 10 sport supplements which contained them to be toxic to the digestive gut microbes of mice.
The study was carried out by Ben-Gurion University of the Negev in Israel and Nanyang Technological University in Singapore.
The artificial sweeteners researchers from the universities focus was on aspartame, sucralose, saccharine, neotame, advantame and acesulfame potassium-k.
Founded in February 2014, 4D Pharma (LON:DDDD) is a world leader in the development of live biotherapeutics, a novel and emerging class of drugs, defined by the FDA as biological products that contain a live organism, such as a bacteria, that is applicable to the prevention, treatment or cure of a disease. 4D has developed a proprietary platform that rationally identifies novel bacteria that have a precise and evolved therapeutic effect. All of 4D’s live biotherapeutic products are orally delivered single strains of bacteria that are naturally found in the healthy human gut. 4D has completed a phase I study in Irritable Bowel Syndrome and has completed dosing in a phase I study in Paediatric Crohn’s Disease. It currently has a pipeline of 13 pre-clinical programmes, covering disease areas such as cancer, poorly controlled asthma, autoimmune and CNS disease, and plans to commence four additional clinical studies in 2018.
