hVIVO selected to conduct large-scale phase 3 Whooping Cough trial

hVIVO plc (LON:HVO), a fast-growing specialist contract research organisation (CRO) and world leader in testing infectious and respiratory disease products using human challenge clinical trials, has announced that it has signed a letter of intent (LOI) with ILiAD Biotechnologies, LLC (ILiAD), to conduct a pivotal Phase 3 human challenge trial for its lead Bordetella pertussis vaccine candidate, BPZE1. ILiAD is a late-stage biotech development company, which has raised over $100m to date, and is dedicated to the prevention of whooping cough, a life-threatening disease caused by Bordetella pertussis. hVIVO and ILiAD are currently working to finalise the definitive agreement, a further announcement will be made in due course.

Highlights

·   hVIVO has been selected to conduct a large-scale Phase 3 human challenge trial (“HCT”) for ILiAD Biotechnologies’ lead Bordetella pertussis (whooping cough) vaccine candidate, BPZE1

·    World’s first pivotal Phase 3 human challenge trial in Bordetella pertussis 

·    Expanding hVIVO’s human challenge model portfolio

·    Expected to be Company’s largest HCT to date

·    Trial expected to commence H2 2025

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