hVIVO plc (LON:HVO), a fast-growing specialist contract research organisation (CRO) and world leader in testing infectious and respiratory disease products using human challenge clinical trials, has announced that it has signed a letter of intent (LOI) with ILiAD Biotechnologies, LLC (ILiAD), to conduct a pivotal Phase 3 human challenge trial for its lead Bordetella pertussis vaccine candidate, BPZE1. ILiAD is a late-stage biotech development company, which has raised over $100m to date, and is dedicated to the prevention of whooping cough, a life-threatening disease caused by Bordetella pertussis. hVIVO and ILiAD are currently working to finalise the definitive agreement, a further announcement will be made in due course.
Highlights
· hVIVO has been selected to conduct a large-scale Phase 3 human challenge trial (“HCT”) for ILiAD Biotechnologies’ lead Bordetella pertussis (whooping cough) vaccine candidate, BPZE1
· World’s first pivotal Phase 3 human challenge trial in Bordetella pertussis
· Expanding hVIVO’s human challenge model portfolio
· Expected to be Company’s largest HCT to date
· Trial expected to commence H2 2025