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Poolbeg Pharma plc presents POLB 001 pre-clinical study data at the 66th ASH meeting

Poolbeg Pharma plc (LON: POLB), a clinical-stage biopharmaceutical company focused on the development and commercialisation of innovative medicines targeting diseases with a high unmet medical need, has announced key insights from its poster presentation at the 66th American Society of Hematology (ASH) Annual Meeting and Exposition, San Diego, California.

The poster, which detailed POLB 001 as a promising preventative therapy for Cytokine Release Syndrome (CRS) associated with cancer immunotherapies, was presented by the Company’s Chief Executive Officer, Jeremy Skillington, PhD on Saturday 7 December.

The study was designed to evaluate the effect of POLB 001 on CRS compared to Adalimumab, an anti-TNF antibody which is a gold standard potent inhibitor of CRS in humanised tumour-bearing mouse models. Mice were treated twice daily with either placebo or POLB 001 at low, medium, or high doses for five days.

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