hVIVO Omicron human challenge agent has been successfully manufactured

hVIVO plc (LON:HVO), (formerly Open Orphan plc) a rapidly growing specialist contract research organisation (CRO) and world leader in testing infectious and respiratory disease products using human challenge clinical trials, has announced that its Omicron human challenge agent has been successfully manufactured.

Subject to the successful completion of the characterisation study and receipt of relevant regulatory approvals, this has expanded the Company’s unique portfolio to 11 human challenge models to test a broad range of infectious and respiratory disease products. hVIVO actively offers Omicron human challenge trials as part of its service offering and is currently in discussions with a number of existing and potential customers.

As announced on 30 June 2022, the model was developed with Vaxart Inc., (NASDAQ: VXRT) with the intent to conduct a subsequent Omicron human challenge study to test the efficacy of Vaxart’s oral vaccine candidate. The Company notes the announcement from Vaxart and its decision to postpone further clinical trials in its COVID-19 programme, including the challenge study, as they focus upon the development of an oral pan-betacoronavirus vaccine, which may provide improved protection against SARS-CoV-2 as the virus continues to mutate and protection against other types of betacoronaviruses.

The Vaxart challenge study was not included in the Company’s order book and its postponement will have no impact on hVIVO’s 2023 financial guidance. As at 31 December 2022 the Company’s orderbook was £76m, with over 95% of forecasted revenue for 2023 contracted.

Click to view all articles for the EPIC: ,
Or click to view the full company profile:
    Share on facebook
    Facebook
    Share on twitter
    Twitter
    Share on linkedin
    LinkedIn
    hVIVO plc

    More articles like this

    hVIVO plc

    hVIVO’s Dr Andrew Catchpole on conducting challenge trials

    Introducing Dr Catchpole As Chief Scientific Officer, Dr Catchpole has “overall responsibility for the scientific conduct” of hVIVO’s studies and laboratory services, and oversees the manufacturing of their challenge viruses. He runs the team that designs the studies

    hVIVO plc

    The people who get paid to get sick

    hVIVO plc (formerly Open Orphan plc) is a rapidly growing specialist contract research organisation (CRO) and the world leader in testing infectious and respiratory disease vaccines and antivirals using human challenge clinical trials, providing end-to-end early clinical development services

    hVIVO plc

    Case study: Non-clinical consultancy

    IntroductionA small sized pharmaceutical company, who had already performed proof-of-concept studies with a small molecule drug candidate came to Venn Life Sciences with the aim to bring their product into clinic as soon as possible. ChallengesThe company’s first

    hVIVO plc

    Advancing of novel antimalarial drug and vaccine candidates

    The Challenge Malaria is a serious and life-threatening, mosquito borne disease prevalent across much of tropical and sub-tropical Asia, South America and Sub-Saharan Africa. Due to increasing resistance to current antimalarial regimens, new drugs are required as both

    hVIVO plc

    hVIVO Annual Report and Accounts now available

    hVIVO plc (LON:HVO), (formerly Open Orphan plc) a rapidly growing specialist contract research organisation (CRO) and world leader in testing infectious and respiratory disease products using human challenge clinical trials, has confirmed that the Company’s Annual Report and Accounts for

    hVIVO plc

    hVIVO transformative year with revenue up 30% to £50.7m

    hVIVO plc (LON:HVO), (formerly Open Orphan plc) a rapidly growing specialist contract research organisation (CRO) and world leader in testing infectious and respiratory disease products using human challenge clinical trials, has announced its audited results for the 12 months

    hVIVO plc

    What is RSV – Understanding the Virus

    Everybody knows what the common cold and influenza are, but we’d guess not many have heard of RSV (Respiratory Syncytial Virus). So, what it is? Well, it is a very common virus that leads to mild, cold like

    hVIVO plc

    hVIVO at World Vaccine Congress Washington 2023

    Chief Scientific Officer, Andrew Catchpole discusses hVIVO’s attendance at the World Vaccine Congress in Washington. hVIVO plc (formerly Open Orphan plc) is a rapidly growing specialist contract research organisation (CRO) and the world leader in testing infectious and respiratory

    hVIVO plc

    hVIVO to publish results on 25 April 2023

    hVIVO plc (LON:HVO), (formerly Open Orphan plc) a rapidly growing specialist contract research organisation (CRO) and world leader in testing infectious and respiratory disease products using human challenge clinical trials, has announced that it will release its audited final

    hVIVO plc

    Advantages to centralising laboratory services at hVIVO

    Clinical field studies are a critical part of the drug development and approval process. They are conducted to evaluate the safety, immunogenicity, and efficacy of a new drug. These studies require careful monitoring, attention to detail, significant logistics,

    hVIVO plc

    Positive results from hVIVO study of Cidara flu candidate

    hVIVO – a company focused on testing global infectious and respiratory disease products through clinical trials – has recorded positive interim results from its study involving Cidara Therapeutics’ CD388 influenza therapy. hVIVO is currently conducting the wider phase

    hVIVO plc

    Venn Life Sciences new offices at Leiden BioScience Park

    hVIVO plc (formerly Open Orphan plc) is a rapidly growing specialist contract research organisation (CRO) and the world leader in testing infectious and respiratory disease vaccines and antivirals using human challenge clinical trials, providing end-to-end early clinical development services

    No more posts to show