hVIVO plc (LON: HVO), a fast-growing specialist contract research organisation (CRO) and world leader in testing infectious and respiratory disease products using human challenge clinical trials, has announced that it has successfully completed a pilot characterisation study for its human metapneumovirus (hMPV) strain A2 challenge agent, demonstrating proof-of-concept for a future hVIVO hMPV challenge model to test new vaccines and antivirals.
Highlights
· hVIVO successfully completes pilot hMPV characterisation study
· Study exhibited strong infectivity rate and induced symptomatic disease in healthy volunteers
· Now marketing for hMPV challenge trials to support the development of hMPV vaccines and antivirals
· Dr Andrew Catchpole to present data from the study at the 13th International RSV Symposium in Brazil
The pilot study, which took place at the Company’s state-of-the-art quarantine facility in Canary Wharf, produced a safe, measurable and reproducible disease in healthy volunteers with strong rates of infection and symptomatic disease. This study confirms that the Company has a viable hMPV human challenge model which can be used in future human challenge trials to support the development of hMPV vaccines and antivirals to meet this unmet medical need. The Company is now marketing its hMPV challenge model and will look to complete the remainder of the characterisation study with a partner in advance of completing future human challenge trials.
