What is the function of a pH buffer?

In vitro, the pH is generally maintained between 7.2 and 7.4.  All Vitrolife media are formulated to meet this narrow pH specification range, supporting optimal metabolic conditions. Maintaining a defined and physiological pH is through the inclusion of certain chemical components in the media called “pH buffers”. These pH buffers act as a weak acid or base. As a result, solutions containing such buffers can resist a change in pH caused by environmental changes.

The most commonly used pH buffer in IVF culture media is bicarbonate, which is the same buffer that is present in our blood. Carbon dioxide (CO2) in the atmosphere surrounding the culture dish will dissolve and equilibrate in the medium.

JPMorgan European Discovery Trust plc (LON:JEDT) is an investment trust company. The Investment Trust JEDT objective is to achieve capital growth from a portfolio of quoted smaller companies in Europe, excluding the United Kingdom.

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