What is a human challenge study?
In a human challenge study, healthy volunteers are intentionally infected with a virus/bacteria or parasite in a quarantine facility. The volunteers are monitored under 24/7 supervision by medical experts. These trials are strictly regulated and approved by the applicable regulators and ethics committee. These studies are performed to help further scientific research and drug development.
Human challenge studies allow for data collection in a controlled environment, this data gives further insights to see if a vaccine or antiviral is effective and contributes to a deeper understanding of how an infectious disease affects a group of volunteers in a controlled medical environment.
hVIVO plc (formerly Open Orphan plc) is a rapidly growing specialist contract research organisation (CRO) and the world leader in testing infectious and respiratory disease vaccines and antivirals using human challenge clinical trials, providing end-to-end early clinical development services for its broad and long-standing client base of biopharma companies.
