The BJA recently published the FEDORA RCT of 420 patients. The study’s statistically significant results reinforce the UK’s NICE recommendation to use oesophageal Doppler monitor (ODM).
Now, TopMedTalk, disseminator of medical news, has reviewed the paper in its Journal Club, hosted by Professor Monty Mythen of UCL, London.
You can listen to the review here, or enjoy some highlights, as follows:
A multicentre, randomised controlled study, FEDORA concluded that:
- Haemodynamic Optimisation significantly reduced post-op complications and length of stay in low to moderate risk patients undergoing major abdominal surgery
- Goal-Directed Haemodynamic Therapy is beneficial even in low to moderate risk patients.
Prof Mythen points out that the Cochrane collaboration has identified 70 prospective, randomised controlled trials on this subject. Moreover, every time meta-analysis has been performed, the result is broadly the same.
Deltex Managing Director Andy Mears states; “FEDORA is a landmark study: It is the first RCT showing outcome benefit in patients having low to moderate abdominal surgery using a GDHT protocol that is only achievable using the ODM. We’re grateful to the clinicians involved for delivering such a complete study, and to Prof Mythen for such a comprehensive review on TopMedTalk.”
