This paper reviews the basic research regarding the molecular mechanism of CBD’s action with particular focus on its analgesic potential for chronic pain treatment, as well as describing the detailed analgesic and anti-inflammatory effects of CBD in various models, including neuropathic pain, inflammatory pain, osteoarthritis and others.
The referenced studies indicate a positive influence of CBD in treatment for various diseases in both pre-clinical and clinical trials. In the majority of animal studies, CBD has been demonstrated to exert analgesic effects, diminishing hyperalgesia and mechanical/thermal allodynia through various routes of administration. In arthritic in vitro studies, CBD promoted chondrocyte and synoviocyte apoptosis but with stronger effects on the inflammatory-activated cells, which may be a positive result that indicates anti-arthritic activity.
Sativa Wellness Group (AQSE:SWEL) goal is to be recognised as one of the leading health companies, through building the best wellness brands in CBD testing services and products, to meet today’s fast evolving consumer expectations. Through full vertical integration of their supply chain and expansion of their distribution network, they plan to become one of the premier producers and high-quality distributors of CBD and wellness products and services in Europe.