A phase 2 trial of Allergy Therapeutics’ grass pollen candidate met its primary endpoint of showing a dose-response relationship. With the trial also establishing a recommended dose of the short-course subcutaneous allergen-specific immunotherapy, Allergy is set to move into phase 3 next year.
Sites in Europe enrolled 447 patients in the clinical trial and randomized them to receive one of four treatment regimens or placebo. Investigators assessed the effect of the regimens by performing a conjunctival provocation test and monitoring the change in allergic symptoms. That showed a relationship between dose and response, the p value for which was less than 0.0001.
Allergy Therapeutics plc (LON:AGY) is a market-leading, pioneering immunology business with specialist experience in the research and development of allergy treatments.